Postmenopausal Hook Effect

"High-dose hook effect" with the Centocor CA 125 assay.

Is the fish-hook effect in hydrocyclones a real phenomenon?

Supplemental Information: Cooperative Binding Mitigates the High-Dose Hook Effect

In order to explore how the high-dose Hook effect is dependent on the parameters used in our model, we repeated the simulations done for the figure entitled “Reduced hook effect in cooperative (wt) calmodulin” with a range of parameter values. First, we varied all dissociation constants by factors of 10. The results (see figure 1) show that a high-dose Hook effect is observed in all the cases. ...

Molar pregnancy with false negative urine hCG: the hook effect.

Urine pregnancy tests are widely used in emergency departments as the first screening test for patients of reproductive age presenting with gynaecological problems in order to rule out pregnancy. Conditions such as complete molar pregnancy, which produces large amounts of beta human chorionic gonadotropin (beta-hCG), may cause a false negative result due to an oversaturation of the assay system...

Misdiagnosis due to the hook effect in prolactin assay.

OBJECTIVES To describe a patient who was misdiagnosed as having a nonfunctional pituitary tumor due to the hook effect on prolactin measurements. CLINICAL PRESENTATION AND INTERVENTION A 45-year-old female was admitted with visual disturbances, panhypopituitarism and central diabetes insipidus due to pituitary tumor recurrence. She had been operated 4 times earlier and received cranial irradi...